Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy

Here we present the ‘Abstract‘ of the corresponding paper by Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, Brandhorst S, Cappello F, Mirzaei H, Lee C, Longo VD. Continue reading “Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy”

Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression

Here we present the ‘Summary‘ of the corresponding paper by Chia-Wei Cheng, Gregor B. Adams, Laura Perin, Min Wei, Xiaoying Zhou, Ben S. Lam, Stefano Da Sacco, Mario Mirisola, David I. Quinn, Tanya B. Dorff, John J. Kopchick, and Valter D. Longo. Continue reading “Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression”

The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results

The idea that organisms can live longer, healthier lives by sharply reducing their calorie intake is not exactly new. Laboratory research has repeatedly demonstrated the anti-aging value of calorie restriction, often called CR, in animals from nematodes to rats—with the implication that the same might be true for humans. Continue reading “The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results”

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